Back row (L to R): Cathie Garnis, Mike Gorenchtein, Shevaun Hughes
Front row (L to R): Becki Towle, Angie Chu
(Picture taken on 15th floor of the BC Cancer Research Centre.)
Happy New (School) Year!
•9 September 2010 • Comments OffGarnis Lab Research Technician: Angie Chu
•9 September 2010 • Comments Off
The Garnis Lab welcomes Angie Chu into the fold. She will be working as a research technician at the BC Cancer Research Centre and contributing to the UBC Division of Otolaryngology via assistance to the Temporal Bone Laboratory. We are pleased to have her join the team. Welcome Angie!
BRF2 is a lineage-specific marker for lung squamous cell carcinoma and is increasingly activated during lung cancer progression
•29 July 2010 • Comments OffA new paper in PLoS Medicine identifies BRF2 as an oncogene specific to lung squamous cell carcinoma, providing a marker to distinguish between subgroups of non-small cell lung cancer. Moreover, work in this paper shows how BRF2 is increasingly activated as disease progresses from premalignant stages to invasive cancer. Dr. Garnis contributed to this broad work, spearheaded by Dr. Will Lockwood.
Parallel molecular analysis of different disease stages – and different histological subgroups of disease – is yielding important insights into the mechanisms that drive cancer initiation and progression. Ultimately, genes like BRF2 may become targets for the next generation of therapies that are tailored against individual tumors.
Lockwood WW, Chari R, Coe BP, Thu KL, Garnis C, Malloff CA, Campbell J, Williams AC, Hwang D, Zhu CQ, Buys TPH, Yee J, English JC, MacAulay C, Tsao MS, Gazdar AF, Minna JD, Lam S, Lam WL. (2010) Integrative Genomic Analyses Identify BRF2 as a Novel Lineage-Specific Oncogene in Lung Squamous Cell Carcinoma. PLoS Med 7(7): e1000315. (link)
Scholarship from the Canadian Institutes of Health Research (Master’s Award: Frederick Banting and Charles Best Canada Graduate Scholarships)
•15 July 2010 • Comments Off
Congratulations to Shevaun on receiving a CIHR CGS Masters Award for the Feb 2010 competition! The title of the funded project is “Identification of Causal Genetic Events in Oral Cancer Progression”. Further details about the project can be found be searching under the Investigator tab at this link.
The Garnis Lab would also like to extend its sincere thanks to the CIHR for its continued support of graduate research efforts!
Support from the Canadian Institutes of Health Research (Spring 2010 Competition, Cancer Progression & Therapeutics Panel)
•5 July 2010 • Comments Off
The Garnis Lab would like to acknowledge recent support provided by the Canadian Institutes of Health Research. This funding has been given for a project entitled ‘Deciphering and reconstituting genetic events in oral cancer progression’. The CIHR has generously provided a 4 year Operating Grant to move this work forwards.
Details on the CIHR can be found here.
